diff --git a/compiler/optimizing/code_generator_arm.cc b/compiler/optimizing/code_generator_arm.cc
index 98577d6..f45aa66 100644
--- a/compiler/optimizing/code_generator_arm.cc
+++ b/compiler/optimizing/code_generator_arm.cc
@@ -6440,8 +6440,9 @@
                         reg,
                         method_reg,
                         ArtMethod::DexCacheResolvedMethodsOffset(kArmPointerSize).Int32Value());
-      // temp = temp[index_in_cache]
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // temp = temp[index_in_cache];
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
       __ LoadFromOffset(kLoadWord, reg, reg, CodeGenerator::GetCachePointerOffset(index_in_cache));
       break;
     }
diff --git a/compiler/optimizing/code_generator_arm64.cc b/compiler/optimizing/code_generator_arm64.cc
index 491014d..f401bda 100644
--- a/compiler/optimizing/code_generator_arm64.cc
+++ b/compiler/optimizing/code_generator_arm64.cc
@@ -3705,7 +3705,8 @@
              MemOperand(method_reg.X(),
                         ArtMethod::DexCacheResolvedMethodsOffset(kArm64WordSize).Int32Value()));
       // temp = temp[index_in_cache];
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
     __ Ldr(reg.X(), MemOperand(reg.X(), GetCachePointerOffset(index_in_cache)));
       break;
     }
diff --git a/compiler/optimizing/code_generator_mips.cc b/compiler/optimizing/code_generator_mips.cc
index 8b19f84..bbfdb30 100644
--- a/compiler/optimizing/code_generator_mips.cc
+++ b/compiler/optimizing/code_generator_mips.cc
@@ -3896,8 +3896,9 @@
                         reg,
                         method_reg,
                         ArtMethod::DexCacheResolvedMethodsOffset(kMipsPointerSize).Int32Value());
-      // temp = temp[index_in_cache]
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // temp = temp[index_in_cache];
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
       __ LoadFromOffset(kLoadWord,
                         reg,
                         reg,
diff --git a/compiler/optimizing/code_generator_mips64.cc b/compiler/optimizing/code_generator_mips64.cc
index 2f9eca6..08e18e6 100644
--- a/compiler/optimizing/code_generator_mips64.cc
+++ b/compiler/optimizing/code_generator_mips64.cc
@@ -3110,8 +3110,9 @@
                         reg,
                         method_reg,
                         ArtMethod::DexCacheResolvedMethodsOffset(kMips64PointerSize).Int32Value());
-      // temp = temp[index_in_cache]
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // temp = temp[index_in_cache];
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
       __ LoadFromOffset(kLoadDoubleword,
                         reg,
                         reg,
diff --git a/compiler/optimizing/code_generator_x86.cc b/compiler/optimizing/code_generator_x86.cc
index 715b5be..b6b2ce3 100644
--- a/compiler/optimizing/code_generator_x86.cc
+++ b/compiler/optimizing/code_generator_x86.cc
@@ -4433,8 +4433,9 @@
       // /* ArtMethod*[] */ temp = temp.ptr_sized_fields_->dex_cache_resolved_methods_;
       __ movl(reg, Address(method_reg,
                            ArtMethod::DexCacheResolvedMethodsOffset(kX86PointerSize).Int32Value()));
-      // temp = temp[index_in_cache]
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // temp = temp[index_in_cache];
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
       __ movl(reg, Address(reg, CodeGenerator::GetCachePointerOffset(index_in_cache)));
       break;
     }
diff --git a/compiler/optimizing/code_generator_x86_64.cc b/compiler/optimizing/code_generator_x86_64.cc
index cc46a07..31a8d14 100644
--- a/compiler/optimizing/code_generator_x86_64.cc
+++ b/compiler/optimizing/code_generator_x86_64.cc
@@ -808,8 +808,9 @@
       __ movq(reg,
               Address(CpuRegister(method_reg),
                       ArtMethod::DexCacheResolvedMethodsOffset(kX86_64PointerSize).SizeValue()));
-      // temp = temp[index_in_cache]
-      uint32_t index_in_cache = invoke->GetTargetMethod().dex_method_index;
+      // temp = temp[index_in_cache];
+      // Note: Don't use invoke->GetTargetMethod() as it may point to a different dex file.
+      uint32_t index_in_cache = invoke->GetDexMethodIndex();
       __ movq(reg, Address(reg, CodeGenerator::GetCachePointerOffset(index_in_cache)));
       break;
     }