diff --git a/target/product/core_64_bit.mk b/target/product/core_64_bit.mk
index 971b6bd..e2fc1a6 100644
--- a/target/product/core_64_bit.mk
+++ b/target/product/core_64_bit.mk
@@ -31,3 +31,6 @@
 
 TARGET_SUPPORTS_32_BIT_APPS := true
 TARGET_SUPPORTS_64_BIT_APPS := true
+
+# Disable DEXPREOPT until we have multilib support (bug 14694978).
+WITH_DEXPREOPT := false